Simscan
From FreeBSDwiki
VERY fast, small, lightweight email scanner written in pure C. Works with Trophie (if present), clamav (if present), spamassassin (if present).
The current scanning agent of choice.
You will however need to use a different version of the qmail-queue-custom-error.patch from the one provided in /contrib at inter7.com if you're running a FreeBSD box and have selected all the options I normally select when building Qmail from ports - something about "qqargs" breaks the bone-stock patch.
Here's the fixed patch: File:Qmail-queue-custom-error.patch